top of page

What Is HGH?: Understanding Human Growth Hormone

Updated: Feb 1

In this article, I aim to provide some of the information that I wish I had access to when I was first starting out. Specifically, I will be discussing Human Growth Hormone, or HGH, and how it can help you achieve your bodybuilding goals.



What Are Hormones ?


To fully understand the role of anabolic hormones in bodybuilding, it is important to first understand what hormones are. Simply put, hormones are molecules that are secreted by glands in the body and act as chemical messengers, carrying regulatory messages throughout the body via the bloodstream.


What are hormones in the human body

Hormones are part of the endocrine system, which is comprised of various glands that secrete hormones. These messengers carry specific messages to target receptors, generating a specific action by signaling these receptors. Hormones can be categorized into three main chemical classes: steroid hormones, protein (or polypeptide) hormones, and amine hormones.





Steroid hormones are derived from cholesterol and are characterized by their unique molecular structure, which allows them to easily penetrate cell membranes. Protein or polypeptide hormones are made up of amino acids and are typically water-soluble, meaning they cannot penetrate cell membranes. Finally, amine hormones are derived from the amino acid tyrosine and are characterized by their chemical structure, which contains an amine group.


Understanding the different classes of hormones and how they work is crucial for comprehending the role that anabolic hormones play in bodybuilding. By gaining knowledge of these key hormones and their functions, bodybuilders can create a more effective training and nutrition plan to reach their goals.

 

Now that we know what hormones are, let’s look at HGH or Human Growth Hormone.


HGH, is a protein hormone that is also referred to as GH, or Growth Hormone. This hormone is composed of 191 amino acids and is produced and secreted by somatotropic cells located within the anterior pituitary gland. The production of HGH is regulated through a complex system of feedback mechanisms that respond to various factors such as sleep, nutrition, stress, exercise, and growth hormone itself. Essentially, as HGH is released in response to these factors, it is secreted in a pulsating fashion that varies on an hourly basis.On average, HGH is secreted every 3-5 hours, with up to 70% of the day's concentration being released during the night, primarily between the hours of 11 pm and 2 am. It is important to note that the pulsatile release of HGH is a critical aspect of its function, as this pattern of secretion allows for the hormone to exert its effects on various tissues throughout the body.


What Is HGH Mechanism Of Action?


Human growth hormone (HGH) has several important functions in the body. It is responsible for promoting growth and development, particularly of bones and muscles. In addition to this, HGH also plays a role in fat loss and skin regeneration.

One of the key ways in which HGH stimulates growth is by directly attaching to target cells and generating a response. This response can lead to an increase in muscle mass and bone density, among other things. HGH can also stimulate growth indirectly through the liver. By binding to receptors on the surface of liver cells, HGH can trigger the release of insulin-like growth factor-1 (IGF-1), which is a protein hormone that is similar in structure to insulin.


IGF-1 plays an important role in the uptake of amino acids by muscle fibers and other target cells. This effect is particularly pronounced after a meal when there are higher levels of glucose and amino acids in the bloodstream. HGH promotes growth by using available nutrients to stimulate protein synthesis and cell growth.


Overall, HGH is an important hormone that plays a vital role in promoting growth and development, as well as regulating metabolism. Its effects are felt throughout the body, from the bones and muscles to the liver and beyond. By understanding how HGH works, we can gain a better appreciation for the complex processes that govern our bodies and help us to stay healthy and strong.


Do Levels Decline As We Age ?


In general, HGH levels will increase during childhood, reach their highest levels during puberty, and begin to decrease as we begin to get older. Based on this research - Growth Hormone in Aging


Decreased secretion of human growth hormone over the lifetime


How Does HGH Relate To The Body’s Other Anabolic Hormones?


HGH, testosterone, and insulin are considered the body’s primary anabolic hormones. 

 

Testosterone


Human growth hormone (HGH) has been found to increase levels of testosterone in the body, and it has similar effects to testosterone when it comes to exercise. Both of these hormones play a direct role in protein synthesis, which is essential for muscle growth and repair.



Testosterone is a hormone that is primarily produced in the testes in men, but it is also present in smaller amounts in women. It is responsible for promoting the development of male sexual characteristics, such as facial hair, a deeper voice, and increased muscle mass. Testosterone also plays a key role in protein synthesis, which is why it is often used by bodybuilders and athletes to enhance their performance.


HGH, on the other hand, is produced by the pituitary gland and plays a key role in regulating growth and development. It has been found to increase levels of testosterone in the body, which in turn can lead to increased protein synthesis and muscle growth. HGH also has similar effects to testosterone when it comes to exercise, helping to promote the repair and growth of muscle tissue.


Overall, the relationship between HGH and testosterone is complex and not fully understood. However, it is clear that both of these hormones play a vital role in protein synthesis and muscle growth, making them important for anyone looking to build strength and improve their athletic performance. By understanding how these hormones work, we can better tailor our exercise and nutrition routines to support our goals and achieve optimal health and fitness.


Insulin


Insulin and human growth hormone (HGH) both play important roles in regulating metabolism and promoting muscle growth. However, their effects can be influenced by diet, and it's important to understand how to optimize their release to support our fitness goals.


Insulin is primarily produced in response to the ingestion of carbohydrates, especially simple carbs. When we eat too many carbs throughout the day, we experience multiple insulin spikes, which can lead to excess carbs being stored as fat. However, if we time our carb intake well, we can shuttle nutrients into the muscle cells, which supports recovery and muscle growth.


HGH release can also be influenced by diet, and a high-carb diet can actually reduce its production. Instead, a diet that is higher in protein with moderate amounts of carbs and fat is the best choice for maximum HGH stimulation. By providing our bodies with the nutrients they need to produce HGH, we can support muscle growth and recovery and optimize our overall health and fitness.


In summary, both insulin and HGH play important roles in promoting muscle growth and regulating metabolism, but their effects can be influenced by diet. By understanding how to optimize their release through diet and timing, we can support our fitness goals and achieve optimal health and performance.


Conclusion on what is HGH


It is evident that HGH is one of the body's main anabolic hormones, and can be utilized to enhance muscle growth and fat loss. By utilizing specific training techniques, maximum HGH release can be stimulated. Alongside this, prioritizing healthy sleep habits and utilizing certain supplements can further optimize the body's natural hormonal manipulation efforts.

44 views
bottom of page