Aknetrent 20 mg by Recordati is a pharmaceutical-grade oral capsule containing isotretinoin, available in blister pack format. Isotretinoin is a retinoid - a synthetic derivative of vitamin A - and is one of the most extensively researched compounds for sebaceous gland (oil gland) regulation in dermatological science.

📦 Product Specifications

Manufacturer: Recordati
Form: Oral soft capsule
Molecule: Isotretinoin (retinoid / vitamin A derivative)
Concentration: 20 mg per capsule
Volume: 30 capsules per box
Dosage considerations may vary. Consulting a qualified healthcare professional is recommended.

✔ Key Research Insights

Researched for its ability to significantly reduce sebaceous gland size and oil production - the primary driver of acne formation in the skin
Studied for its effect on skin cell turnover, helping prevent the buildup of dead cells that block pores and create conditions for bacterial growth
Investigated for its anti-inflammatory properties within skin tissue, observed to reduce redness and swelling associated with severe acne lesions
Researched for its long-lasting effects on sebum regulation, with many research subjects maintaining results well beyond the active dosing period

⚙ How It Works Isotretinoin is a vitamin A derivative that works by targeting the root causes of acne at a cellular level. It shrinks the sebaceous glands (the glands in your skin that produce oil) - in some research observations by up to 90% - which dramatically reduces the oily environment that bacteria thrive in. At the same time, it slows down the rate at which skin cells build up inside pores, preventing blockages before they form. It also has a direct anti-inflammatory effect on the skin. Unlike topical compounds that work on the surface, isotretinoin works from the inside out, which is why its effects tend to be more thorough and longer lasting. The compound is fat-soluble, meaning it absorbs better when taken with a meal containing some fat.

⚠ Clinical Considerations

Isotretinoin is associated with significant teratogenic risk (it can cause serious harm to a developing fetus) - strict contraceptive protocols are essential for female research subjects of childbearing potential
Dryness of the skin, lips, and eyes is the most commonly observed side effect and is directly linked to the compound's mechanism of reducing oil production
Liver enzyme levels and blood lipids (cholesterol and triglycerides) should be monitored periodically during any research protocol, as isotretinoin has been observed to affect both
Mood-related observations have been noted in some research subjects - any significant psychological changes during a protocol should be assessed promptly by a qualified professional

⭐ Product Overview

Manufactured by Recordati, a globally recognized European pharmaceutical company operating under stringent GMP-certified standards
Consistent capsule formulation with precise isotretinoin concentration for reliable research dosing
Isotretinoin has over four decades of published dermatological research, making it one of the most studied retinoid compounds available
High manufacturing standards and pharmaceutical-grade quality assurance supporting consistent compound integrity across production batches

Isotretinoin Thailand | Aknetrent / Roaccutane

THB 1,300.00

Quantity

Aknetrent is a prescription retinoid capsule manufactured by Recordati (Turkey), containing 20mg of isotretinoin — a powerful derivative of Vitamin A. It belongs to the same drug class as Accutane and Roaccutane and works by dramatically reducing sebum production, normalizing skin cell turnover, and suppressing the bacteria responsible for severe acne. Aknetrent is specifically indicated for severe nodular or cystic acne that has not responded to other treatments, including antibiotics and topical therapies. It is taken orally once or twice daily with food throughout a treatment course of 16 to 24 weeks.
Aknetrent and Roaccutane contain exactly the same active ingredient - isotretinoin - and produce identical clinical results. The key difference is the manufacturer and price: Roaccutane is the original brand by Roche, while Aknetrent is a certified generic by Recordati, typically available at a significantly lower cost. Both are produced in WHO-certified facilities and meet the same bioavailability standards. For patients in Thailand seeking a cost-effective alternative to Roaccutane without compromising on quality or efficacy, Aknetrent 20mg is a fully equivalent option prescribed and trusted by dermatologists worldwide.
The standard starting dose of Aknetrent is 0.5mg per kilogram of body weight per day — for example, a 70kg patient would begin at 35mg daily. The capsules should always be taken with food to improve absorption and reduce stomach discomfort. Visible improvement typically begins within 2 to 4 weeks, with significant results appearing after 8 to 12 weeks. Many patients achieve long-lasting or permanent remission after completing a full course.
The most common side effects of Aknetrent (isotretinoin) are dryness of the lips, skin, and eyes, which affect nearly all patients. These effects are manageable with moisturizers, lip balms, and staying well hydrated. Less common effects include joint pain, temporary hair thinning, and increased sensitivity to sunlight - always apply SPF 50+ sunscreen during treatment. Isotretinoin is strictly contraindicated during pregnancy due to the risk of severe birth defects - women of childbearing age must use reliable contraception throughout the entire course.